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The Tru Calling Wiki (created May 18, 2009)
The lead character, Tru Davies, (Eliza Dushku), is a young woman working the night shift at the city morgue. Occasionally, the corpse of a newly dead person appears to awaken and utter the words "Help me" to her. As they do, Tru wakens with a start at the beginning of the same day, finding herself compelled to stop the death, which may be the result of anything from suicide to murder. In the course of the re-run day, Tru often takes the opportunity to rectify various personal situations involving family and friends. Supporting characters in the series include Harrison Davies (Shawn Reaves), Tru's irresponsible younger brother (who becomes a loyal asset to Tru by the end of the first season), and Davis (Zach Galifianakis), her friend, confidante, and supervisor at the Morgue. As the series progresses, it is revealed that several years earlier, Davis had a fateful encounter with Tru's mother (who was, apparently, the last person to receive the "calling" before her daughter).

Supporting characters surviving only a portion of the series included (Jessica Collins), Tru's older sister; Lindsay Walker (A. J. Cook), her best friend in the first season; Luc Johnston (Matthew Bomer), her love interest in the first season; and Gardez (Benjamín Benítez), her former co-worker at the morgue. Jack Harper (Jason Preistly), a counterpart to Tru's character, is introduced midseason as a foil. He is there to make sure fate gets its way and introduces a philosophical aspect to Tru's endeavors: should she be saving the lives of people who may have been intended to die? In the second season, Tru and Jack compete to get to a person first — she to save them, and he to restore the order of fate and maintain the balance of the universe as he understands it. It is eventually revealed that Tru's father had played a similarly antagonistic role to Tru's mother.